The French industrial action is due to start on Monday evening and last until Wednesday morning.
Only half of TGV services will be running during the strike, announced France’s rail operator SNCF.
Lyria services to Switzerland are among those affected, with SBB telling passengers to expect disruption.
TGV-Lyria trains link Paris and Dijon to the Swiss cities of Lausanne, Geneva, Zurich and Bern.
Supported by all four French trade unions, the strike is aimed at pressuring SNCF in an ongoing battle over pay and working conditions.
The unions have threatened to carry out further industrial action if their demands are not met.